Delving into Allende's dark secrets

Delving into BioMEMS.

Delving into the diversity of silencing pathways

Submitted 20 March 2007; accepted 22 May 2007; published online 29 June 2007 developments include the elucidation of steps in the biogenesis of repeat-associated small interfering RNAs (rasiRNAs), new ideas about how siRNAs silence gene expression, how miRNAs repress translation, and the importance of siRNAs as tools in biological research and therapeutics. The discovery of siRNAs, which silenc...

Delving into somatic variation in sporadic melanoma.

Melanoma, the most aggressive form of skin cancer, has increased in incidence more rapidly than any other cancer. The completion of the human genome project and advancements in genomics technologies has allowed us to investigate genetic alterations of melanoma at a scale and depth that is unprecedented. Here, we survey the history of the different approaches taken to understand the genomics of ...

Delving deeper into MALT lymphoma biology.

Mucosa-associated lymphoid tissue (MALT) lymphomas can arise in a variety of extranodal sites. Interestingly, at least 3 different, apparently site-specific, chromosomal translocations, all affecting the NF-kappaB pathway, have been implicated in the development and progression of MALT lymphoma. The most common is the translocation t(11;18)(q21;q21), which results in a fusion of the cIAP2 regio...

Delving into the Whorl of Flower Segmentation

We describe an algorithm for automatically segmenting flowers in colour photographs. This is a challenging problem because of the sheer variety of flower classes, the intra-class variability, the variation within a particular flower, and the variability of imaging conditions – lighting, pose, foreshortening etc. The method couples two models – a colour model for foreground and background, and a...